Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.73 |
| ▸ | ESR1 | P03372 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | PGR | P06401 | 3/20 | 0.73 |
| ▸ | AR | P10275 | 3/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527384 | 0.91 | KMT2A (0.71) | LMNAESR1MAPTKMT2ACYP3A4 | |
| SCHEMBL10361012 | 0.91 | LMNA (0.60) | LMNAESR1MAPTKMT2ACYP3A4 | |
| SCHEMBL4619351 | 0.89 | LMNA (0.62) | LMNAESR1MAPTKMT2ACYP3A4 | |
| SCHEMBL4254922 | 0.88 | MAPT (0.58) | LMNAESR1MAPTKMT2ACYP3A4 | |
| SCHEMBL6547189 | 0.88 | MAPT (0.58) | LMNAESR1MAPTKMT2ACYP3A4 | |
| SCHEMBL10710638 | 0.87 | MAPT (0.57) | LMNAESR1MAPTKMT2ACYP3A4 | |
| SCHEMBL10360650 | 0.85 | MAPT (0.60) | LMNAESR1MAPTKMT2ACYP3A4 | |
| Estradiol Valerate SCHEMBL21437462 | 0.84 | LMNA (1.00) | LMNAESR1MAPTKMT2ACYP3A4 | |
| Estradiol Valerate SCHEMBL29772962 | 0.84 | LMNA (1.00) | LMNAESR1MAPTKMT2ACYP3A4 | |
| Estradiol Valerate SCHEMBL40563 | 0.84 | LMNA (1.00) | LMNAESR1MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101252936-A | Pharmaceutically acceptable carrier for ophthalmic compositions | NASCENT PHARMACEUTICAL INC (US) | 2008-08-27 | — | — | CN | disclosed |
| EP-1858522-A4 | PHARMACEUTICALLY ACCEPTABLE CARRIER FOR OPHTHALMIC COMPOSITIONS | NASCENT PHARMACEUTICAL INC (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1858522-A1 | PHARMACEUTICALLY ACCEPTABLE CARRIER FOR OPHTHALMIC COMPOSITIONS | Nascent Pharmaceutical, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| EP-1858523-A1 | COMBINAION THERAPY FOR TOPICAL APPLICATION IN THE TREATMENT OF DRY EYE SYNDROME | Nascent Pharmaceutical, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| US-20060211660-A1 | Combination therapy for topical application in the treatment of dry eye syndrome | ALTOS VISION LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| US-20060210645-A1 | Pharmaceutically acceptable carrier for ophthalmic compositions | ALTOS VISION LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| WO-2006094028-A1 | COMBINAION THERAPY FOR TOPICAL APPLICATION IN THE TREATMENT OF DRY EYE SYNDROME | NASCENT PHARMACEUTICALS, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006094026-A1 | PHARMACEUTICALLY ACCEPTABLE CARRIER FOR OPHTHALMIC COMPOSITIONS | NASCENT PHARMACEUTICALS, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| CN-1404394-A | Composition comprising a metal oxide and a metal oxide | STERIX LTD (GB) | 2003-03-19 | — | — | CN | disclosed |
| US-6096733-A | Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application | Lubkin, Virginia (US) | 2000-08-01 | — | — | US | disclosed |