Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361076 | 0.90 | ALDH1A1 (0.45) | RAB9AKDM4ENPC1ALDH1A1KMT2A | |
| SCHEMBL10361299 | 0.89 | TSHR (0.40) | RAB9AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10360748 | 0.88 | TSHR (0.42) | RAB9AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10360351 | 0.88 | TSHR (0.55) | RAB9AKDM4ENPC1ALDH1A1KMT2A | |
| SCHEMBL10361140 | 0.87 | TSHR (0.45) | KDM4EALDH1A1GAAKMT2ATSHR | |
| SCHEMBL10361362 | 0.87 | NOTUM (0.51) | ALDH1A1KMT2ATSHRMAPTMEN1 | |
| SCHEMBL10361324 | 0.87 | NPSR1 (0.44) | RAB9AKDM4ENPC1ALDH1A1KMT2A | |
| SCHEMBL10361080 | 0.85 | POLB (0.43) | ALDH1A1GAAKMT2ATSHRMAPT | |
| SCHEMBL10360696 | 0.85 | MAPT (0.43) | RAB9AKDM4ENPC1ALDH1A1TSHR | |
| SCHEMBL10360670 | 0.84 | GABRA2 (0.44) | KDM4EALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | claimed |
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |