Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360399 | 0.88 | MAPT (0.44) | MAPTTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10360745 | 0.88 | TSHR (0.40) | MAPTTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10361312 | 0.87 | MAPT (0.56) | MAPTKDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10360706 | 0.86 | MAPT (0.43) | MAPTTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10361327 | 0.86 | NOTUM (0.55) | MAPTTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10360682 | 0.86 | MAPT (0.43) | MAPTTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10360298 | 0.85 | MAPT (0.42) | MAPTKDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10360664 | 0.85 | RAB9A (0.47) | MAPTTSHRKDM4EALDH1A1POLB | |
| SCHEMBL10361124 | 0.83 | MAPT (0.43) | MAPTTSHRKDM4EALDH1A1POLB | |
| SCHEMBL10360378 | 0.83 | PPARD (0.44) | MAPTKDM4EALDH1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | claimed |
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |