Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360696 | 0.88 | MAPT (0.43) | TSHRHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL10360682 | 0.87 | MAPT (0.43) | TSHRHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL10361303 | 0.86 | MAPT (0.40) | TSHRHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL10361299 | 0.84 | TSHR (0.40) | TSHRMAPTNOTUMALDH1A1KDM4E | |
| SCHEMBL10361327 | 0.84 | NOTUM (0.55) | TSHRHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL10361312 | 0.83 | MAPT (0.56) | MAPTALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10361111 | 0.81 | TSHR (0.45) | TSHRHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL10360399 | 0.81 | MAPT (0.44) | TSHRHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL10360303 | 0.80 | HPGD (0.43) | TSHRPOLBSMN1; SMN2 | |
| SCHEMBL10360391 | 0.80 | PPARG (0.37) | HTR2BMAPTALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |