Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558292 | 0.90 | CACNA1C (0.35) | HTR2ASLC6A4KCNH2MAOBMAOA | |
| SCHEMBL10361439 | 0.88 | SLC6A4 (0.34) | SLC6A4MAOBMAOAKMT2AMEN1 | |
| SCHEMBL9558218 | 0.88 | RIPK1 (0.41) | HTR2ASLC6A4 | |
| SCHEMBL9558421 | 0.86 | HTR2A (0.41) | HTR2ASLC6A4KCNH2MAOBMAOA | |
| SCHEMBL9557909 | 0.85 | MEN1 (0.40) | HTR2ASLC6A4KCNH2MAOBMAOA | |
| SCHEMBL9838544 | 0.84 | SLC6A4 (0.37) | HTR2ASLC6A4KCNH2MAOBMAOA | |
| SCHEMBL9029398 | 0.84 | TTR (0.39) | HTR2ASLC6A4KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL10837041 | 0.83 | MAPT (0.43) | HTR2ASLC6A4KCNH2MAOBMAOA | |
| SCHEMBL10836849 | 0.81 | TTR (0.36) | HTR2ASLC6A4KCNH2KDM4EALDH1A1 | |
| SCHEMBL10360900 | 0.81 | CYP4F2 (0.33) | KMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175377-B1 | AN ETHER COMPOUND, ITS PRODUCTION AND AN INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-11-28 | — | — | EP | disclosed |
| US-4664698-A | Ether compound, and an insecticidal and acaricidal composition containing it as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0175377-A2 | An ether compound, its production and an insecticidal and acaricidal composition containing it as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-03-26 | — | — | EP | disclosed |