SCHEMBL9557909

SCHEMBL9557909

COc1ccc(Oc2cc(COCC(C)(C)c3ccc(Cl)cc3)ccc2F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 3/20 0.39
HTT P42858 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
HTR2A P28223 2/20 0.38
SLC6A4 P31645 2/20 0.38
KCNH2 Q12809 2/20 0.38
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
MAPT P10636 2/20 0.36
NPBWR1 P48145 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558013 0.92 RAB9A (0.38) KMT2ALMNARAB9AL3MBTL1SMN1; SMN2
SCHEMBL9558421 0.92 HTR2A (0.41) HTR2ASLC6A4KCNH2GRIN2DGRIN3B
SCHEMBL9558435 0.91 TTR (0.40) HTTKCNH2RAB9AL3MBTL1SMN1; SMN2
SCHEMBL9838544 0.90 SLC6A4 (0.37) HTR2ASLC6A4KCNH2GRIN2DGRIN3B
SCHEMBL9029398 0.89 TTR (0.39) LMNAHTTNPSR1HTR2ASLC6A4
SCHEMBL10837041 0.89 MAPT (0.43) MEN1KMT2ALMNAHTTNPSR1
SCHEMBL10360768 0.85 HTR2A (0.39) MEN1KMT2AHTR2ASLC6A4KCNH2
SCHEMBL9558237 0.85 SLC6A4 (0.40) HTR2ASLC6A4KCNH2L3MBTL1MAOB
SCHEMBL10837117 0.84 NPC1 (0.38) MEN1KMT2ARAB9A
SCHEMBL10835453 0.83 MAPT (0.44) LMNASLC6A4RAB9AL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed