SCHEMBL9558292

SCHEMBL9558292

CC(C)(C)COCc1ccc(F)c(Oc2ccc(F)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 1/20 0.35
SLC6A4 P31645 5/20 0.35
MAOB P27338 4/20 0.35
HTR2A P28223 3/20 0.35
KCNH2 Q12809 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A3 Q01959 2/20 0.35
LPAR1 Q92633 1/20 0.34
LPAR5 Q9H1C0 1/20 0.34
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
POLB P06746 1/20 0.33
MAOA P21397 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360768 0.90 HTR2A (0.39) SLC6A4MAOBHTR2AKCNH2SLC6A2
SCHEMBL10361439 0.89 SLC6A4 (0.34) SLC6A4MAOBSLC6A2SLC6A3LPAR1
SCHEMBL9558218 0.89 RIPK1 (0.41) SLC6A4HTR2ALPAR1LPAR5
SCHEMBL9558013 0.85 RAB9A (0.38) MAOBLPAR1LPAR5POLB
SCHEMBL9558421 0.85 HTR2A (0.41) SLC6A4MAOBHTR2AKCNH2SLC6A2
SCHEMBL9557935 0.85 SLC6A4 (0.37) SLC6A4MAOBHTR2AKCNH2
SCHEMBL10837314 0.83 HTR2A (0.38) SLC6A4MAOBHTR2ALPAR1LPAR5
SCHEMBL9559005 0.83 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3
SCHEMBL9558493 0.83 CACNA1C (0.44) CACNA1CSLC6A4MAOBSLC6A2SLC6A3
SCHEMBL9558357 0.83 PPARA (0.32) CACNA1CSLC6A4HTR2AKCNH2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed