SCHEMBL10360769

SCHEMBL10360769

Fc1ccc(COCC(Cl)(Cl)Cl)nc1Oc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.34
RAB9A P51151 1/20 0.34
MAPT P10636 2/20 0.33
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33
GRM5 P41594 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
PIN1 Q13526 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361865 0.90 RAB9A (0.33) KCNH2RAB9AMAPTCYSLTR2CYSLTR1
SCHEMBL10362297 0.89 POLB (0.34) KCNH2RAB9AMAPTKDM4EMEN1
SCHEMBL10362092 0.87 P2RX3 (0.34) LMNAHTTKDM4EMEN1HPGD
SCHEMBL10794841 0.87 CYP1A2 (0.36) RAB9AMAPTKDM4EMEN1HPGD
SCHEMBL10362175 0.86 KCNH2 (0.34) KCNH2RAB9AMAPTCYSLTR2CYSLTR1
SCHEMBL9516090 0.85 RAB9A (0.32) KCNH2RAB9AMAPTCYSLTR2CYSLTR1
SCHEMBL10362164 0.84
SCHEMBL9682569 0.83 RAB9A (0.32) KCNH2RAB9AMAPTCYSLTR2CYSLTR1
SCHEMBL10362173 0.82 RARG (0.34) LMNAKDM4E
SCHEMBL10361870 0.78 SLC6A4 (0.39) KCNH2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175377-B1 AN ETHER COMPOUND, ITS PRODUCTION AND AN INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-28 EP disclosed
US-4664698-A Ether compound, and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-12 US disclosed
EP-0175377-A2 An ether compound, its production and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed