SCHEMBL10362175

SCHEMBL10362175

CC(C)(C)COCc1ccc(F)c(Oc2ccccc2)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.34
RIPK1 Q13546 1/20 0.34
RAB9A P51151 1/20 0.34
MAPT P10636 4/20 0.33
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
LTA4H P09960 1/20 0.32
FFAR1 O14842 1/20 0.31
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
PLG P00747 2/20 0.31
PLAU P00749 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361865 0.90 RAB9A (0.33) KCNH2RIPK1RAB9AMAPTCYSLTR2
SCHEMBL10362066 0.89 CYP1A2 (0.36) MAPTKDM4EHPGDCYP1A2CYP2C9
SCHEMBL9682569 0.88 RAB9A (0.32) KCNH2RAB9AMAPTCYSLTR2CYSLTR1
SCHEMBL10360159 0.88 CYP1A2 (0.37) RAB9AMAPTLTA4HFFAR1KDM4E
SCHEMBL10362158 0.88 POLB (0.36) KCNH2MAPTKDM4EHPGDCYP1A2
SCHEMBL10794985 0.88 P2RX3 (0.35) RAB9AHTTKDM4EHPGDCYP1A2
SCHEMBL9516090 0.87 RAB9A (0.32) KCNH2RIPK1RAB9AMAPTCYSLTR2
SCHEMBL10361376 0.87 ALDH1A1 (0.36) RAB9AMAPTLMNAKDM4EHPGD
SCHEMBL10360744 0.87 ABCG2 (0.31)
SCHEMBL10360769 0.86 KCNH2 (0.34) KCNH2RAB9AMAPTCYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175377-B1 AN ETHER COMPOUND, ITS PRODUCTION AND AN INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-28 EP disclosed
US-4664698-A Ether compound, and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-12 US disclosed
EP-0175377-A2 An ether compound, its production and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed