SCHEMBL9681472

SCHEMBL9681472

CC(C)(CCl)COCc1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.43
RIPK1 Q13546 1/20 0.38
LPAR1 Q92633 7/20 0.36
LPAR5 Q9H1C0 7/20 0.36
TACR1 P25103 1/20 0.35
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10655931 0.89 TTR (0.38) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL9683220 0.89 TTR (0.38) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL10346789 0.88 TTR (0.40) TTRLPAR1LPAR5TACR1FFAR4
SCHEMBL10361908 0.87 TTR (0.42) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL9558218 0.87 RIPK1 (0.41) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL10654097 0.85 TTR (0.39) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL10837667 0.85 TACR1 (0.42) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL10361910 0.84 TTR (0.40) TTRLPAR1LPAR5FFAR4
SCHEMBL10439067 0.83 TTR (0.39) TTRRIPK1LPAR1LPAR5TACR1
SCHEMBL10836737 0.83 TTR (0.39) TTRRIPK1LPAR1LPAR5TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093373-A PHENOXY-BENZYL ETHER COMPOUNDS, COMPOSITIONS CONTAINING SAME, AND INSECTICIDAL METHOD OF USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-03-03 US disclosed
US-5006538-A Application to rice plants SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-04-09 US disclosed
EP-0315916-A2 Ether compound, a method for producing it, a composition containing it as an active ingredient and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-17 EP disclosed
US-4792563-A Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-20 US disclosed
EP-0266891-A1 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP disclosed