Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.52 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362381 | 0.83 | LMNA (0.56) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10361975 | 0.76 | LMNA (0.65) | LMNAKMT2AALDH1A1POLBCA1 | |
| SCHEMBL17976248 | 0.74 | DRD4 (0.47) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10362411 | 0.74 | LMNA (0.58) | LMNAKMT2AALDH1A1POLB | |
| SCHEMBL4491465 | 0.73 | DRD4 (0.49) | LMNAALDH1A1OPRK1 | |
| SCHEMBL9184019 | 0.73 | LMNA (0.47) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL10767314 | 0.72 | LMNA (0.56) | LMNAKMT2AALDH1A1POLB | |
| SCHEMBL17976220 | 0.70 | OPRK1 (0.49) | POLBOPRD1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL9775427 | 0.70 | LMNA (0.60) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL17549667 | 0.70 | SLC6A4 (0.67) | LMNAKMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | claimed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | claimed |
| EP-0207901-A1 | Antianaphylactic and antibronchospastic N-benzhydryldiazacycloalkylalkananilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1987-01-07 | — | — | EP | claimed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | disclosed |
| EP-0207901-A1 | Antianaphylactic and antibronchospastic N-benzhydryldiazacycloalkylalkananilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1987-01-07 | — | — | EP | disclosed |