SCHEMBL10362147

SCHEMBL10362147

CC(=O)CCCc1ccc[nH]1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.37
IAPP P10997 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PARP1 P09874 1/20 0.35
PARP10 Q53GL7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4170437 0.95 ALDH1A1 (0.40) ALDH1A1TSHRIAPPHDAC3HDAC4
SCHEMBL10362176 0.89 ALDH1A1 (0.48) ALDH1A1TSHRIAPPHTTSMN1; SMN2
SCHEMBL736098 0.83 HDAC3 (0.52) ALDH1A1TSHRHDAC3HDAC4HDAC1
SCHEMBL7878183 0.83 MPO (0.42) ALDH1A1TSHRHDAC3HDAC4HDAC1
SCHEMBL10449197 0.82 ALDH1A1 (0.39) ALDH1A1TSHRIAPPHTTSMN1; SMN2
SCHEMBL10449018 0.82 ALDH1A1 (0.39) ALDH1A1TSHRIAPPHTTSMN1; SMN2
SCHEMBL28372818 0.81 TSHR (0.45) ALDH1A1TSHRHTTSMN1; SMN2
SCHEMBL23135892 0.77 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL7003873 0.77 GPR84 (0.41) GPR84
SCHEMBL1471746 0.76 MAPT (0.55) TSHRHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0097881-B1 SUBSTITUTED AZOLYL KETONES AND ALCOHOLS BAYER AG (DE) 1990-08-29 EP disclosed
US-4747869-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1988-05-31 US disclosed
EP-0097882-A2 Keto-aldehyde derivatives and process for their preparation BAYER AG (DE) 1984-01-11 EP disclosed