Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10537534 | 0.99 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBADRA2C | |
| Hydrochloric Acid SCHEMBL10537421 | 0.86 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10541994 | 0.85 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10538936 | 0.81 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL10362189 | 0.75 | HDAC6 (0.48) | ADRA2C | |
| SCHEMBL10362748 | 0.75 | HDAC6 (0.64) | ADRA2C | |
| SCHEMBL10696223 | 0.74 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10537811 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| SCHEMBL9844130 | 0.69 | CYP11B1 (0.57) | CYP19A1CYP11B1CYP11B2POLBADRA2C | |
| SCHEMBL15179016 | 0.69 | CYP11B1 (0.76) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257171-A1 | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1988-03-02 | — | — | EP | claimed |