Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FOXO1 | Q12778 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804146 | 0.85 | MEN1 (0.48) | TGM2ITKMEN1CYP1A2CYP3A4 | |
| SCHEMBL10362506 | 0.82 | CYP1A2 (0.48) | TGM2ZDHHC20ZDHHC2ITKMEN1 | |
| SCHEMBL10363150 | 0.81 | HDAC6 (0.50) | TGM2ZDHHC20ZDHHC2ITKMEN1 | |
| SCHEMBL10806368 | 0.80 | TGM2 (0.47) | TGM2ZDHHC20ZDHHC2ITKKMT2A | |
| SCHEMBL10364043 | 0.78 | TGM2 (0.50) | TGM2ZDHHC20ZDHHC2ITKMEN1 | |
| SCHEMBL10804531 | 0.78 | TGM2 (0.52) | TGM2ZDHHC20ZDHHC2ITKKMT2A | |
| SCHEMBL10812618 | 0.77 | ZDHHC20 (0.47) | TGM2ZDHHC20ZDHHC2MEN1CYP1A2 | |
| SCHEMBL10364076 | 0.77 | MAPT (0.44) | TGM2ITKMEN1KMT2AKDM4E | |
| SCHEMBL10806297 | 0.77 | CYP1A2 (0.44) | TGM2ZDHHC20ZDHHC2MEN1CYP1A2 | |
| SCHEMBL10803446 | 0.76 | TGM2 (0.56) | TGM2ZDHHC20ZDHHC2ITKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |