Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805757 | 0.85 | TGM2 (0.40) | MAPTKMT2ATDP1LMNATGM2 | |
| SCHEMBL10363273 | 0.80 | RAB9A (0.56) | MAPTKMT2AMEN1LMNATGM2 | |
| SCHEMBL10806413 | 0.77 | TGM2 (0.41) | MAPTTDP1TGM2ALDH1A1KDM4E | |
| SCHEMBL10363150 | 0.77 | HDAC6 (0.50) | MAPTKMT2AMEN1HPGDTGM2 | |
| SCHEMBL10364011 | 0.77 | TGM2 (0.45) | KMT2AMEN1TGM2ALDH1A1ITK | |
| SCHEMBL10805912 | 0.76 | ALDH1A1 (0.42) | MAPTKMT2ATDP1TGM2ALDH1A1 | |
| SCHEMBL10806368 | 0.76 | TGM2 (0.47) | KMT2AHPGDTGM2ALDH1A1ITK | |
| SCHEMBL11021174 | 0.76 | ERN1 (0.44) | MAPTKMT2AMEN1TDP1LMNA | |
| SCHEMBL10808157 | 0.76 | TGM2 (0.41) | MAPTKMT2AMEN1HPGDLMNA | |
| SCHEMBL10729530 | 0.76 | CTSB (0.43) | MAPTKMT2AMEN1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |