Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807361 | 0.92 | TGM2 (0.42) | AURKAAURKBKMT2ABRCA1KDM4E | |
| SCHEMBL10802603 | 0.87 | KMT2A (0.43) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL10805774 | 0.82 | TGM2 (0.43) | AURKAAURKBKMT2ABRCA1TGM2 | |
| SCHEMBL10810349 | 0.81 | TGM2 (0.42) | KMT2AKDM4EALDH1A1TGM2GAA | |
| SCHEMBL10804942 | 0.80 | KCNA3 (0.51) | KMT2AKDM4EALDH1A1TTRTGM2 | |
| SCHEMBL10818993 | 0.78 | GAA (0.54) | KMT2AKDM4EALDH1A1L3MBTL1TGM2 | |
| SCHEMBL10362443 | 0.78 | GAA (0.49) | KMT2AKDM4EALDH1A1TGM2SMN1; SMN2 | |
| SCHEMBL10363161 | 0.77 | TGM2 (0.51) | KMT2AKDM4EALDH1A1MAPTTGM2 | |
| SCHEMBL10805447 | 0.77 | TGM2 (0.42) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL10803446 | 0.77 | TGM2 (0.56) | KMT2AKDM4EALDH1A1MEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |