Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807361 | 0.89 | TGM2 (0.42) | TGM2GAAKMT2AKCNA3ITK | |
| SCHEMBL10805774 | 0.83 | TGM2 (0.43) | TGM2GAAKMT2AZDHHC20ZDHHC2 | |
| SCHEMBL10802603 | 0.83 | KMT2A (0.43) | TGM2GAAKMT2AKCNA3ITK | |
| SCHEMBL10806769 | 0.82 | TGM2 (0.39) | TGM2GAAKMT2AKCNA3ITK | |
| SCHEMBL10364062 | 0.81 | AURKA (0.43) | TGM2GAAKMT2AKCNA3ITK | |
| SCHEMBL10804942 | 0.81 | KCNA3 (0.51) | TGM2GAAKMT2AKCNA3ITK | |
| SCHEMBL10805447 | 0.80 | TGM2 (0.42) | TGM2GAAKMT2AKCNA3ITK | |
| SCHEMBL10818993 | 0.79 | GAA (0.54) | TGM2GAAKMT2AITKKDM4E | |
| SCHEMBL11036931 | 0.79 | PGAM1 (0.42) | TGM2ALDH1A1 | |
| SCHEMBL10803446 | 0.78 | TGM2 (0.56) | TGM2GAAKMT2AITKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |