Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.54 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362588 | 0.96 | THRB (0.58) | TGM2ZDHHC20ZDHHC2THRBALDH1A1 | |
| SCHEMBL10363871 | 0.95 | ZDHHC20 (0.58) | TGM2ZDHHC20ZDHHC2THRBALDH1A1 | |
| SCHEMBL10364375 | 0.94 | ALDH1A1 (0.59) | TGM2ZDHHC20ZDHHC2THRBALDH1A1 | |
| SCHEMBL10805451 | 0.92 | ZDHHC2 (0.63) | TGM2ZDHHC20ZDHHC2NPC1RAB9A | |
| SCHEMBL19855999 | 0.91 | THRB (0.51) | TGM2ZDHHC20ZDHHC2THRBALDH1A1 | |
| SCHEMBL10806934 | 0.91 | ZDHHC2 (0.66) | ZDHHC20ZDHHC2 | |
| SCHEMBL10806059 | 0.89 | ZDHHC2 (0.69) | TGM2ZDHHC20ZDHHC2 | |
| SCHEMBL10806715 | 0.89 | ZDHHC2 (0.69) | TGM2ZDHHC20ZDHHC2 | |
| SCHEMBL10808118 | 0.89 | ZDHHC2 (0.69) | TGM2ZDHHC20ZDHHC2 | |
| SCHEMBL19854531 | 0.89 | THRB (0.59) | TGM2ZDHHC20ZDHHC2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |