Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23383209 | 0.83 | KDM4E (0.51) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL27154650 | 0.79 | KDM4E (0.61) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL8388879 | 0.78 | NPC1 (0.70) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL8931082 | 0.78 | NPC1 (0.70) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL30887130 | 0.76 | KDM4E (0.53) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6387107 | 0.75 | HPGD (0.66) | GAAKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1193924 | 0.72 | NPC1 (0.71) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL1193922 | 0.72 | NPC1 (0.71) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL23873951 | 0.71 | ESR1 (0.56) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL5517096 | 0.70 | KDM4E (0.49) | NPC1RAB9AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151884-B1 | LIQUID DETERGENT COMPOSITIONS | Albright & Wilson Limited (GB) | 1990-04-18 | — | — | EP | disclosed |