Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039000 | 0.87 | LMNA (0.63) | LMNATP53POLBMAPTMEN1 | |
| SCHEMBL10364777 | 0.86 | LMNA (0.62) | LMNATP53POLBMAPTMEN1 | |
| SCHEMBL1883906 | 0.78 | ALDH1A1 (0.66) | LMNATP53POLBMAPTMEN1 | |
| SCHEMBL6864831 | 0.78 | LMNA (0.57) | LMNATP53POLBMAPTMEN1 | |
| SCHEMBL6883427 | 0.77 | PTPN1 (0.64) | LMNATP53MAPTMEN1ALDH1A1 | |
| SCHEMBL7031824 | 0.76 | LMNA (0.46) | LMNATP53POLBMAPTKMT2A | |
| SCHEMBL7029041 | 0.76 | KDM4E (0.44) | LMNATP53POLBMAPTKMT2A | |
| SCHEMBL7031240 | 0.76 | KDM4E (0.44) | LMNATP53POLBMAPTMEN1 | |
| SCHEMBL7026006 | 0.75 | MAPT (0.44) | LMNATP53POLBMAPTMEN1 | |
| SCHEMBL7034000 | 0.75 | KDM4E (0.43) | LMNATP53POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161211-B1 | N-HETEROCYCLOSULFONYL-N'-PYRIMIDINYL AND -TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | disclosed |
| US-4932997-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0161211-A1 | N-heterocyclosulfonyl-N'-pyrimidinyl and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |