Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 2/20 | 0.47 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624007 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10364587 | 0.83 | NPC1 (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10362887 | 0.82 | NPC1 (0.48) | ALDH1A1NPC1RAB9AMAPTDDX3X | |
| SCHEMBL8369698 | 0.81 | ALDH1A1 (0.76) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10362722 | 0.79 | POLB (0.57) | ALDH1A1NPC1RAB9AMAPTPOLB | |
| SCHEMBL403705 | 0.78 | CA12 (0.64) | ALDH1A1RAB9AMAPTCISD2CA12 | |
| SCHEMBL3529435 | 0.77 | KDM4E (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL70172 | 0.75 | CA12 (0.59) | RAB9AMAPTCA12CA1CA2 | |
| SCHEMBL14401688 | 0.75 | ALDH1A1 (0.60) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9686399 | 0.75 | ALDH1A1 (0.60) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |