SCHEMBL9686399

SCHEMBL9686399

[CH2]c1c(C)cccc1NC(=O)NC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
RECQL P46063 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
POLB P06746 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
DDX3X O00571 2/20 0.47
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
HPGD P15428 2/20 0.43
ITGB3 P05106 2/20 0.42
ITGAV P06756 2/20 0.42
ITGB1 P05556 1/20 0.42
ITGA5 P08648 1/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ANPEP P15144 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28767450 0.84 DDX3X (0.46) ALDH1A1RECQLSMN1; SMN2POLBDDX3X
SCHEMBL9686605 0.81 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2POLBDDX3XNPC1
SCHEMBL8369698 0.81 ALDH1A1 (0.76) ALDH1A1RECQLSMN1; SMN2POLBDDX3X
SCHEMBL9685670 0.80 POLB (0.54) ALDH1A1RECQLSMN1; SMN2POLBTDP1
SCHEMBL5839856 0.79 HPGD (0.49) ALDH1A1POLBDDX3XNPC1RAB9A
SCHEMBL14401688 0.79 ALDH1A1 (0.60) ALDH1A1RECQLSMN1; SMN2POLBTDP1
SCHEMBL9685750 0.79 NPC1 (0.53) ALDH1A1SMN1; SMN2POLBTDP1DDX3X
SCHEMBL9685656 0.77 HPGD (0.48) ALDH1A1SMN1; SMN2POLBNPC1RAB9A
SCHEMBL9687479 0.77 HPGD (0.47) ALDH1A1SMN1; SMN2POLBNPC1RAB9A
SCHEMBL14003501 0.76 ALDH1A1 (1.00) ALDH1A1RECQLSMN1; SMN2POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed