Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364534 | 0.86 | S100B (0.36) | L3MBTL1TSHRCYP19A1NQO2ALDH1A1 | |
| SCHEMBL10568294 | 0.84 | TSHR (0.50) | L3MBTL1TSHRCYP19A1NQO2ALDH1A1 | |
| SCHEMBL10366983 | 0.78 | TSHR (0.49) | TSHRCYP19A1NQO2ALDH1A1MAPT | |
| SCHEMBL10366982 | 0.78 | TSHR (0.49) | TSHRCYP19A1NQO2ALDH1A1MAPT | |
| SCHEMBL10725957 | 0.76 | PDGFRB (0.45) | ALDH1A1MAPTHTT | |
| SCHEMBL10569299 | 0.74 | ALDH1A1 (0.51) | TSHRALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL10564660 | 0.73 | CYP19A1 (0.47) | L3MBTL1TSHRCYP19A1NQO2ALDH1A1 | |
| SCHEMBL10567603 | 0.70 | KDM4E (0.42) | L3MBTL1TSHRCYP19A1ALDH1A1MAPT | |
| SCHEMBL10566461 | 0.70 | CYP19A1 (0.49) | L3MBTL1TSHRCYP19A1NQO2ALDH1A1 | |
| SCHEMBL10565552 | 0.69 | ALDH1A1 (0.44) | L3MBTL1TSHRCYP19A1NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166564-B1 | PYRIMIDONE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-01-31 | — | — | EP | disclosed |
| US-4649142-A | 3,4-dihydro-1,3-disubstituted-6-(substituted phenylimino)-2(1H)-pyrimidinone useful as cardiotonic agent and anti-allergic agent | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0166564-A2 | Pyrimidone derivatives, preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |