SCHEMBL10364645

SCHEMBL10364645

CC(=O)NC(C)n1ccnc1C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP26A1 O43174 1/20 0.37
FPR2 P25090 4/20 0.33
KMT2A Q03164 1/20 0.33
MTNR1A P48039 3/20 0.32
MTNR1B P49286 3/20 0.32
ACACB O00763 1/20 0.32
FDPS P14324 1/20 0.31
GRM5 P41594 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28615774 0.85 CYP26A1 (0.36) CYP26A1FPR2KMT2AFDPSGRM5
SCHEMBL27972693 0.78 CYP26A1 (0.32) CYP26A1
SCHEMBL10688674 0.73 ALDH1A1 (0.44) CYP26A1FPR2FDPS
SCHEMBL2962693 0.72 CYP26A1 (0.42) CYP26A1FPR2GRM5
SCHEMBL27902709 0.72 CYP26A1 (0.37) CYP26A1FPR2FDPSGRM5
SCHEMBL9210148 0.71
SCHEMBL15917807 0.71
SCHEMBL273629 0.71
SCHEMBL8928043 0.71 CYP26A1 (0.43) CYP26A1FPR2KMT2AFDPS
Oxalic Acid SCHEMBL10364074 0.70 CYP26A1 (0.38) CYP26A1FPR2FDPSGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0239246-B1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR SYNTHESIS THEREOF, AND METHOD OF CURING EPOXY RESINS USING SAID COMPOUNDS SHIKOKU CHEMICALS CORPORATION (JP) 1990-05-16 EP claimed
EP-0239246-A1 Novel imidazole compounds, process for synthesis thereof, and method of curing epoxy resins using said compounds SHIKOKU CHEMICALS CORPORATION (JP) 1987-09-30 EP claimed
JP-62198668-A None JP disclosed
EP-0239246-B1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR SYNTHESIS THEREOF, AND METHOD OF CURING EPOXY RESINS USING SAID COMPOUNDS SHIKOKU CHEMICALS CORPORATION (JP) 1990-05-16 EP disclosed
US-4826991-A Production of 1-aminoethyl-imidazoles via the hydrolysis of 1-acylaminoethylimidazoles SHIKOKU CHEMICALS CORPORATION (JP) 1989-05-02 US disclosed
EP-0239246-A1 Novel imidazole compounds, process for synthesis thereof, and method of curing epoxy resins using said compounds SHIKOKU CHEMICALS CORPORATION (JP) 1987-09-30 EP disclosed
JP-S62198668-A NOVEL IMIDAZOLE COMPOUND, SYNTHESIS THEREOF AND CURING OF POLYEPOXY RESIN USING SAID COMPOUND SHIKOKU CHEM CORP 1987-09-02 JP disclosed