Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | ALPG | P10696 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688674 | 0.82 | ALDH1A1 (0.44) | CYP26A1FPR2ALDH1A1FDPSSMN1; SMN2 | |
| SCHEMBL315254 | 0.78 | CYP26A1 (0.40) | CYP26A1ALDH1A1FDPSALPLALPG | |
| Oxalic Acid SCHEMBL10364074 | 0.76 | CYP26A1 (0.38) | CYP26A1FPR2ALDH1A1FDPSSMN1; SMN2 | |
| SCHEMBL21629869 | 0.74 | — | — | |
| SCHEMBL3554565 | 0.73 | CYP26A1 (0.42) | CYP26A1KMT2AMEN1 | |
| SCHEMBL15917807 | 0.72 | — | — | |
| SCHEMBL9210148 | 0.72 | — | — | |
| SCHEMBL273629 | 0.72 | — | — | |
| SCHEMBL19182926 | 0.71 | NR3C2 (0.39) | CYP26A1KMT2A | |
| SCHEMBL10364645 | 0.71 | CYP26A1 (0.37) | CYP26A1FPR2FDPSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458901-B1 | INHIBITING TRANSFORMATION OF CELLS HAVING ELEVATED PURINE METABOLIC ENZYME ACTIVITY | MASSACHUSETTS INST TECHNOLOGY (US) | 1997-12-17 | — | — | EP | claimed |