Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429016 | 0.81 | APEX1 (0.41) | KMT2AMEN1POLBLMNAKDM4E | |
| SCHEMBL20506744 | 0.79 | APEX1 (0.46) | KMT2AMEN1POLBLMNAKDM4E | |
| SCHEMBL10363086 | 0.77 | APEX1 (0.59) | KMT2APOLBLMNAKDM4EALDH1A1 | |
| SCHEMBL9632580 | 0.75 | APEX1 (0.42) | POLBLMNAKDM4EALDH1A1PTGS1 | |
| SCHEMBL27085582 | 0.74 | LMNA (0.59) | KMT2AMEN1POLBLMNARXFP1 | |
| SCHEMBL10435601 | 0.74 | APEX1 (0.36) | KMT2AMEN1POLBLMNAKDM4E | |
| SCHEMBL9633100 | 0.73 | SMN1; SMN2 (0.41) | KMT2AMEN1POLBNOTUMHDAC1 | |
| SCHEMBL10363209 | 0.72 | SMN1; SMN2 (0.45) | KMT2AMEN1POLBLMNAKDM4E | |
| SCHEMBL10435181 | 0.72 | KDM4E (0.38) | KMT2AMEN1POLBLMNAKDM4E | |
| SCHEMBL10363686 | 0.71 | LMNA (0.57) | KMT2AMEN1LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228447-A4 | PESTICIDAL POLYHALOALKENE DERIVATIVES | — | 1990-12-27 | — | — | EP | claimed |
| US-4952580-A | NEMATOCIDES, ANTHELMINTICS | FMC CORPORATION (US) | 1990-08-28 | — | — | US | claimed |
| EP-0228447-A1 | PESTICIDAL POLYHALOALKENE DERIVATIVES | FMC Corporation (US) | 1987-07-15 | — | — | EP | claimed |
| WO-1986007590-A1 | PESTICIDAL POLYHALOALKENE DERIVATIVES | FMC CORPORATION (US) | 1986-12-31 | — | — | WO | claimed |
| EP-0228447-A4 | PESTICIDAL POLYHALOALKENE DERIVATIVES | — | 1990-12-27 | — | — | EP | disclosed |
| US-4952580-A | NEMATOCIDES, ANTHELMINTICS | FMC CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |
| EP-0228447-A1 | PESTICIDAL POLYHALOALKENE DERIVATIVES | FMC Corporation (US) | 1987-07-15 | — | — | EP | disclosed |
| WO-1986007590-A1 | PESTICIDAL POLYHALOALKENE DERIVATIVES | FMC CORPORATION (US) | 1986-12-31 | — | — | WO | disclosed |