Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364751 | 0.81 | KMT2A (0.52) | APEX1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10363086 | 0.80 | APEX1 (0.59) | APEX1ALDH1A1KMT2ANPSR1HTT | |
| SCHEMBL20506744 | 0.79 | APEX1 (0.46) | APEX1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10428940 | 0.74 | APEX1 (0.52) | APEX1ALDH1A1KMT2ANPSR1HTT | |
| SCHEMBL10362960 | 0.72 | APEX1 (0.50) | APEX1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10363208 | 0.72 | APEX1 (0.50) | APEX1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10363686 | 0.71 | LMNA (0.57) | APEX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10363048 | 0.69 | TERT (0.51) | APEX1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL20506750 | 0.69 | ALDH1A1 (0.52) | APEX1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL20506738 | 0.69 | GAA (0.50) | APEX1ALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952580-A | NEMATOCIDES, ANTHELMINTICS | FMC CORPORATION (US) | 1990-08-28 | — | — | US | claimed |