Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364500 | 0.85 | DRD2 (0.43) | TGM2MAPTALDH1A1GAAPDK2 | |
| SCHEMBL10362462 | 0.82 | HDAC1 (0.54) | TGM2ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL10809452 | 0.82 | KDM4E (0.51) | TGM2ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL10805447 | 0.81 | TGM2 (0.42) | TGM2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL10808817 | 0.81 | ZDHHC20 (0.51) | TGM2ALDH1A1NPC1RAB9AGAA | |
| SCHEMBL11017478 | 0.81 | HDAC1 (0.53) | TGM2ALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL10363148 | 0.80 | TGM2 (0.58) | TGM2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10362406 | 0.79 | TGM2 (0.60) | TGM2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10363983 | 0.79 | TGM2 (0.60) | TGM2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10362464 | 0.79 | TGM2 (0.60) | TGM2ALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |