Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366994 | 0.87 | SIRT3 (0.47) | EIF4ECCNCCDK8CYP19A1GPBAR1 | |
| SCHEMBL10364884 | 0.85 | ALDH1A1 (0.40) | CCNCCDK8CYP19A1GPBAR1SIRT3 | |
| SCHEMBL10365986 | 0.82 | XDH (0.39) | GPBAR1 | |
| SCHEMBL5736185 | 0.78 | CDC7 (0.46) | MAPTCDC7DBF4 | |
| SCHEMBL10090913 | 0.77 | CYP3A4 (0.50) | GPR35 | |
| SCHEMBL10367445 | 0.73 | CDK8 (0.44) | CCNCCDK8GPBAR1SIRT3TDP1 | |
| SCHEMBL10367425 | 0.72 | SIRT3 (0.48) | CCNCCDK8GPBAR1SIRT3TDP1 | |
| SCHEMBL3401795 | 0.72 | KDM4E (0.54) | — | |
| SCHEMBL10365737 | 0.72 | CYP11B1 (0.40) | CYP19A1GPBAR1ABL1PDE2APDE10A | |
| SCHEMBL10367437 | 0.71 | SIRT3 (0.40) | CCNCCDK8GPBAR1SIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199968-B1 | THIAZOLE DERIVATIVES | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | claimed |