Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.44 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367005 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1MAPTSPRPOLB | |
| SCHEMBL10366974 | 0.87 | HSD11B1 (0.56) | KDM4EALDH1A1CNR1MAPTCNR2 | |
| SCHEMBL10365365 | 0.87 | ALDH1A1 (0.69) | KDM4EALDH1A1MAPTSPRPOLB | |
| SCHEMBL10367091 | 0.85 | CNR1 (0.55) | ALDH1A1CNR1CNR2POLBHSD11B1 | |
| SCHEMBL10367046 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10365394 | 0.83 | CNR1 (0.69) | CNR1CNR2SPR | |
| SCHEMBL2851938 | 0.83 | SPR (0.56) | KDM4EALDH1A1CNR1MAPTCNR2 | |
| SCHEMBL2852540 | 0.83 | KDM4E (0.66) | KDM4EALDH1A1MAPTSPRPOLB | |
| SCHEMBL10366508 | 0.82 | CNR1 (0.52) | KDM4EALDH1A1CNR1CNR2SPR | |
| SCHEMBL10366939 | 0.81 | PDE4B (0.50) | CNR1MAPTCNR2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |