Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479165 | 0.84 | AGXT (0.49) | TDP1KDM4EMAPK1RAB9ANPC1 | |
| SCHEMBL30189577 | 0.82 | KDM4E (0.54) | TDP1KDM4EMAPK1GAAL3MBTL1 | |
| SCHEMBL3310045 | 0.82 | KDM4E (0.54) | TDP1KDM4EMAPK1GAAL3MBTL1 | |
| Naphthalene SCHEMBL27740230 | 0.80 | CA1 (0.42) | TDP1GAAL3MBTL1ALDH1A1HTT | |
| Naphthalene SCHEMBL27760899 | 0.80 | CA2 (0.39) | TDP1MAPK1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL470925 | 0.79 | TDP1 (0.68) | TDP1KDM4EMAPK1RAB9ANPC1 | |
| SCHEMBL29666114 | 0.79 | TDP1 (0.68) | TDP1KDM4EMAPK1RAB9ANPC1 | |
| SCHEMBL13666949 | 0.79 | KDM4E (0.42) | TDP1KDM4EMAPK1RAB9ANPC1 | |
| SCHEMBL27881561 | 0.79 | L3MBTL1 (0.59) | TDP1MAPK1GAAL3MBTL1RAB9A | |
| SCHEMBL3310123 | 0.78 | MEN1 (0.52) | TDP1KDM4EMAPK1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276717-A1 | PURIFICATION STRATEGY FOR DIRECT NUCLEOPHILIC PROCEDURES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009127372-A1 | PURIFICATION STRATEGY FOR DIRECT NUCLEOPHILIC PROCEDURES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |