SCHEMBL3310045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30189577	1.00	KDM4E (0.54)	KDM4ETDP1MAPK1NPC1RAB9A
	SCHEMBL6276180	0.92	KDM4E (0.61)	KDM4ETDP1MAPK1NPC1RAB9A
	Busulfan SCHEMBL16337522	0.82	KDM4E (0.65)	KDM4EALDH1A1LMNACA1CA2
	SCHEMBL29429997	0.82	TDP1 (0.76)	KDM4ETDP1MAPK1NPC1RAB9A
	SCHEMBL1859481	0.82	TDP1 (0.76)	KDM4ETDP1MAPK1NPC1RAB9A
	SCHEMBL28499516	0.82	KDM4E (0.56)	KDM4ETDP1MAPK1NPC1RAB9A
	SCHEMBL1036616	0.82	TDP1 (0.49)	KDM4ETDP1MAPK1NPC1RAB9A
	SCHEMBL4741970	0.81	KCNA3 (0.56)	KDM4EDRD3ALDH1A1HDAC1LMNA
	SCHEMBL16478997	0.80	KDM4E (0.50)	KDM4ETDP1MAPK1NPC1RAB9A
	SCHEMBL30176806	0.80	PDE10A (0.52)	KDM4ETDP1NPC1RAB9ADRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.