Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TYMP | P19971 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513029 | 0.88 | LMNA (0.38) | SMN1; SMN2L3MBTL1LMNAHTTMAPK1 | |
| SCHEMBL4993123 | 0.85 | GCGR (0.38) | SMN1; SMN2L3MBTL1LMNAHTTMAPK1 | |
| SCHEMBL12495812 | 0.84 | L3MBTL1 (0.40) | SMN1; SMN2L3MBTL1LMNAHTTMAPK1 | |
| SCHEMBL12661856 | 0.80 | L3MBTL1 (0.38) | SMN1; SMN2L3MBTL1LMNAHTTMAPK1 | |
| SCHEMBL10368091 | 0.80 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL10366340 | 0.80 | ALDH1A1 (0.41) | LMNATLR8ALDH1A1TLR7KMT2A | |
| SCHEMBL4986988 | 0.76 | TLR8 (0.55) | L3MBTL1LMNATLR8TLR7MAPT | |
| SCHEMBL6419045 | 0.76 | TLR8 (0.55) | L3MBTL1LMNATLR8TLR7MAPT | |
| SCHEMBL30917377 | 0.75 | HTT (0.36) | SMN1; SMN2L3MBTL1LMNAHTTMAPK1 | |
| SCHEMBL12650427 | 0.75 | HTT (0.36) | SMN1; SMN2L3MBTL1LMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191443-B1 | 4-AMINO-PYRIMIDINES AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0191443-A2 | 4-Amino-pyrimidines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1986-08-20 | — | — | EP | disclosed |