Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393977 | 0.89 | KDM4E (0.67) | KDM4EGAASIGMAR1HTR1ADRD4 | |
| SCHEMBL11402886 | 0.88 | KDM4E (0.69) | KDM4EGAASIGMAR1HTR1ADRD4 | |
| SCHEMBL18754269 | 0.85 | KDM4E (0.75) | KDM4EGAASIGMAR1HTR1ADRD4 | |
| SCHEMBL14067276 | 0.85 | DRD4 (0.61) | KDM4EGAAALDH1A1SIGMAR1HTR1A | |
| SCHEMBL13079491 | 0.83 | KDM4E (0.78) | KDM4EGAASIGMAR1HTR1ADRD4 | |
| SCHEMBL8102656 | 0.83 | KDM4E (0.63) | KDM4EGAAALDH1A1SIGMAR1HTR1A | |
| SCHEMBL4400393 | 0.81 | KDM4E (0.61) | KDM4EGAAALDH1A1HSD17B10SIGMAR1 | |
| SCHEMBL2093634 | 0.81 | KDM4E (0.61) | KDM4EGAAALDH1A1SIGMAR1HTR1A | |
| SCHEMBL82832 | 0.81 | MAPT (0.61) | SIGMAR1HTR1AHTR7DRD2MAPT | |
| SCHEMBL6150880 | 0.81 | MAPT (0.62) | KDM4EGAAALDH1A1HSD17B10SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094159-B1 | DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4892875-A | HYPOTENSIVE, RENAL VASODILATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0094159-A1 | Dihydropyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-16 | — | — | EP | disclosed |
| US-4147790-A | (4-Phenyl-piperazino alkyl)-3-benzoyl-benzene alkanoates | ROUSSEL UCLAF (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4017623-A | Esters of 2-[(4-quinolyl)amino]-benzoic acids in analgesic and anti-inflammatory compositions | SYNTHELABO (FR) | 1977-04-12 | — | — | US | disclosed |
| US-3935229-A | ANALGESIC, ANTIINFLAMMATORY | SYNTHELABO (FR) | 1976-01-27 | — | — | US | disclosed |