Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.56 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505011 | 0.87 | SMN1; SMN2 (0.58) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL19372016 | 0.83 | UBE2T (0.70) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL9474218 | 0.83 | KDM4E (0.61) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL10367346 | 0.82 | SMN1; SMN2 (0.71) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL1412767 | 0.82 | SMN1; SMN2 (0.64) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL6240191 | 0.80 | UBE2T (0.61) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL29595720 | 0.80 | KDM4E (0.58) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL9641726 | 0.80 | SMN1; SMN2 (0.70) | HTTSMN1; SMN2RAB9ANPC1ALOX15 | |
| SCHEMBL28795915 | 0.77 | SMN1; SMN2 (0.69) | KDM4ETDP1HTTGAAALDH1A1 | |
| SCHEMBL12511 | 0.77 | UBE2T (0.61) | KDM4ETDP1HTTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165537-B1 | PROCESS FOR THE PREPARATION OF HETEROARYLOXYACETAMIDES | BAYER AG (DE) | 1990-01-17 | — | — | EP | claimed |
| CN-102070563-B | Method for preparing 2-benzothiazolylethyl sulfone | UNIV ZHEJIANG | 2012-06-06 | — | — | CN | disclosed |
| CN-102070563-B | Method for preparing 2-benzothiazolylethyl sulfone | UNIV ZHEJIANG | 2012-06-06 | — | — | CN | disclosed |
| CN-102070563-B | Method for preparing 2-benzothiazolylethyl sulfone | UNIV ZHEJIANG | 2012-06-06 | — | — | CN | disclosed |
| CN-102070563-A | Method for preparing 2-benzothiazolylethyl sulfone | UNIV ZHEJIANG | 2011-05-25 | — | — | CN | disclosed |
| CN-102070563-A | Method for preparing 2-benzothiazolylethyl sulfone | UNIV ZHEJIANG | 2011-05-25 | — | — | CN | disclosed |
| CN-102070563-A | Method for preparing 2-benzothiazolylethyl sulfone | UNIV ZHEJIANG | 2011-05-25 | — | — | CN | disclosed |