Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 3/20 | 0.35 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.34 |
| ▸ | MERTK | Q12866 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367530 | 0.85 | METAP1 (0.39) | ALDH1A1GLAGAAKDM4EMETAP1 | |
| SCHEMBL10368710 | 0.79 | TACR3 (0.43) | CYP1A2CYP2C9TACR3 | |
| SCHEMBL10371119 | 0.78 | ADORA1 (0.50) | ADORA1ALDH1A1GLAGAAKDM4E | |
| SCHEMBL10367538 | 0.78 | ADORA1 (0.50) | ADORA1ALDH1A1GLAGAAKDM4E | |
| SCHEMBL10368263 | 0.77 | METAP1 (0.39) | ALDH1A1GLAGAAKDM4EMETAP1 | |
| SCHEMBL9529639 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TP53GLAGAAKDM4E | |
| SCHEMBL10533280 | 0.73 | LMNA (0.47) | ALDH1A1TP53CYP1A2GLAGAA | |
| SCHEMBL10368162 | 0.71 | METAP1 (0.37) | ALDH1A1TP53GLAGAAKDM4E | |
| Phosphoric Acid SCHEMBL9531941 | 0.71 | POLB (0.36) | ALDH1A1KDM4EMETAP1TACR3POLB | |
| SCHEMBL10369840 | 0.70 | POLB (0.36) | ALDH1A1KDM4EMETAP1GCGRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4711888-A | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0210044-A2 | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-01-28 | — | — | EP | disclosed |