Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367949 | 0.92 | METAP1 (0.35) | METAP1ALDH1A1POLBMAPTLMNA | |
| Phosphoric Acid SCHEMBL10367955 | 0.86 | GAA (0.36) | METAP1POLBMAPTLMNAMEN1 | |
| SCHEMBL9528551 | 0.85 | POLB (0.38) | METAP1ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9528690 | 0.85 | NPSR1 (0.38) | METAP1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9529639 | 0.85 | ALDH1A1 (0.39) | METAP1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9528238 | 0.84 | POLB (0.37) | METAP1ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9527618 | 0.84 | PKM (0.38) | METAP1ALDH1A1KDM4EPOLBLMNA | |
| Dimethylamine SCHEMBL9528899 | 0.84 | ALDH1A1 (0.34) | METAP1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL10368263 | 0.83 | METAP1 (0.39) | METAP1ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9528360 | 0.83 | RAB9A (0.36) | METAP1ALDH1A1KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | claimed |
| US-4711888-A | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-12-08 | — | — | US | claimed |
| EP-0210044-A2 | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-01-28 | — | — | EP | claimed |
| EP-0210044-B1 | HYDROXY AND ALKOXY PYRIMIDINES | PFIZER INC. (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4711888-A | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0210044-A2 | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-01-28 | — | — | EP | disclosed |