Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.65 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998153 | 0.99 | EPHX2 (0.66) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL8998286 | 0.92 | EPHX2 (0.56) | EPHX2NR1H4CYSLTR2CYSLTR1LMNA | |
| SCHEMBL8901046 | 0.88 | CYSLTR2 (0.64) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9479001 | 0.86 | CYSLTR1 (0.60) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9478778 | 0.85 | CYSLTR2 (0.54) | EPHX2NR1H4CYSLTR2CYSLTR1LMNA | |
| SCHEMBL8998132 | 0.85 | CYSLTR2 (0.52) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9478986 | 0.85 | EPHX2 (0.66) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL8951214 | 0.84 | CYSLTR2 (0.62) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9479016 | 0.84 | CYSLTR2 (0.61) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL10558787 | 0.84 | CYSLTR2 (0.50) | EPHX2NR1H4CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179619-B1 | HETEROCYCLIC AMIDES | ICI AMERICAS INC. (US) | 1990-09-05 | — | — | EP | claimed |
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | claimed |