Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998153 | 0.89 | EPHX2 (0.66) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL10368401 | 0.88 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1 | |
| SCHEMBL10368754 | 0.88 | EPHX2 (0.65) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8899898 | 0.83 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8951214 | 0.82 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998286 | 0.82 | EPHX2 (0.56) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8951165 | 0.82 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL9479233 | 0.82 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951422 | 0.81 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951233 | 0.79 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997005114-A1 | QUINOLONE SULFONIMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |