Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616801 | 0.81 | GAA (0.61) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL1441446 | 0.76 | GAA (0.54) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL5084625 | 0.75 | MAPT (0.67) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL5080900 | 0.73 | MAPT (0.64) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL31310566 | 0.72 | L3MBTL1 (0.54) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL30040907 | 0.72 | GAA (0.59) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL15081851 | 0.72 | MAPT (0.53) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL11208844 | 0.72 | GAA (0.59) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL11345559 | 0.72 | GAA (0.53) | GAAALDH1A1TDP1HTTALOX15 | |
| SCHEMBL30102484 | 0.72 | KDM4E (0.37) | GAAALDH1A1HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252507-B1 | 2-(4-PYRIDYLAMINOMETHYL)-BENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | Maruishi Seiyaku Kabushiki Kaisha (JP) | 1990-10-10 | — | — | EP | disclosed |
| US-4818761-A | VIRICIDES FOR COMMON COLD, HEPATITIS, POLIOMYELITIS | MARUISHI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0252507-A1 | 2-(4-Pyridylaminomethyl)-benzimidazole derivatives having antiviral activity | Maruishi Seiyaku Kabushiki Kaisha (JP) | 1988-01-13 | — | — | EP | disclosed |