Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102408 | 0.88 | KCNQ2 (0.36) | KDM4ESMN1; SMN2PTGER4LMNARAB9A | |
| SCHEMBL30102414 | 0.79 | PTGER4 (0.33) | PTGER4ALDH1A1MAPT | |
| SCHEMBL30102413 | 0.79 | HAT1 (0.36) | SMN1; SMN2PTGER4LMNAALDH1A1MAPT | |
| SCHEMBL30102431 | 0.74 | DRD2 (0.44) | KDM4ESMN1; SMN2PTGER4DRD4LMNA | |
| SCHEMBL30102415 | 0.74 | ACHE (0.33) | PTGER4 | |
| SCHEMBL30102382 | 0.72 | HDAC8 (0.46) | KDM4EHDAC6RAB9ANPC1 | |
| SCHEMBL10368992 | 0.72 | GAA (0.50) | KDM4ESMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL413427 | 0.71 | TDP1 (0.56) | KDM4ESMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL18289061 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2HTTLMNARAB9ATSHR | |
| SCHEMBL27883917 | 0.68 | MEN1 (0.44) | KDM4ESMN1; SMN2HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272313-A1 | MODULATORS OF HISTONE ACETYLTRANSFERASE 1 AND METHODS OF TREATMENT THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | disclosed |