Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369146 | 1.00 | MAOB (0.41) | MAOBMIFNSD2BCHEDAO | |
| SCHEMBL9171936 | 0.75 | MAPT (0.41) | NSD2BCHEDAOCES1HPGD | |
| SCHEMBL16559335 | 0.75 | ACHE (0.50) | MAOBNSD2BCHEDAOCES1 | |
| Hydrochloric Acid SCHEMBL10513970 | 0.74 | MAPT (0.40) | NSD2BCHEDAOCES1HPGD | |
| SCHEMBL11485209 | 0.73 | MIF (0.65) | MAOBMIFHPGDKDM4EALDH1A1 | |
| SCHEMBL11485212 | 0.73 | MIF (0.65) | MAOBMIFHPGDKDM4EALDH1A1 | |
| SCHEMBL11492158 | 0.68 | KDM4E (0.55) | MAOBMIFHPGDKDM4EALDH1A1 | |
| SCHEMBL10369274 | 0.68 | MAOB (0.51) | MAOBMIFKDM4EMAOA | |
| SCHEMBL11492156 | 0.68 | KDM4E (0.55) | MAOBMIFHPGDKDM4EALDH1A1 | |
| SCHEMBL10369273 | 0.68 | MAOB (0.51) | MAOBMIFKDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196803-B1 | BENZENE-FUSED HETEROCYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4692444-A | DIURETICS, VASODILATORS, HYPOTENSIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-08 | — | — | US | disclosed |
| EP-0196803-A2 | Benzene-fused heterocyclic compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |