Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | POLR1A | O95602 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371855 | 0.94 | RAD52 (0.44) | HTTKCNH2TOP2APOLR1ARAD52 | |
| SCHEMBL10370459 | 0.82 | KDM4E (0.33) | HTTALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL11099295 | 0.73 | TOP2A (0.43) | HTTTOP2ARAD52KDM4EL3MBTL1 | |
| SCHEMBL11088487 | 0.72 | MEN1 (0.51) | HTTALOX15RAD52KDM4EALDH1A1 | |
| SCHEMBL10872150 | 0.72 | CSNK2A1 (0.51) | HTTTOP2ARAD52KDM4EALDH1A1 | |
| SCHEMBL11099232 | 0.71 | KDM4E (0.51) | HTTALOX15KCNH2TOP2APOLR1A | |
| SCHEMBL10370586 | 0.71 | KDM4E (0.45) | HTTALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10370567 | 0.70 | KDM4E (0.44) | HTTALOX15KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL10369784 | 0.70 | KDM4E (0.46) | HTTALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10871870 | 0.70 | RAD52 (0.45) | HTTALOX15KCNH2RAD52KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234931-B1 | AZAANTHRACENE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234931-A1 | Azaanthracene compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1987-09-02 | — | — | EP | disclosed |