Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370567 | 0.84 | KDM4E (0.44) | KDM4ETSHRALOX15SMN1; SMN2HTT | |
| SCHEMBL10369784 | 0.83 | KDM4E (0.46) | KDM4ETSHRALOX15SMN1; SMN2HTT | |
| SCHEMBL11088487 | 0.82 | MEN1 (0.51) | KDM4ETSHRALOX15SMN1; SMN2HTT | |
| SCHEMBL10369480 | 0.81 | ALDH1A1 (0.35) | KDM4ETSHRALOX15SMN1; SMN2HTT | |
| SCHEMBL10370537 | 0.73 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2HTTALDH1A1KMT2A | |
| SCHEMBL11079267 | 0.71 | KMT2A (0.40) | KDM4ESMN1; SMN2HTTALDH1A1KMT2A | |
| SCHEMBL10370461 | 0.71 | HTT (0.45) | KDM4EALOX15HTTALDH1A1HSD17B10 | |
| SCHEMBL10371855 | 0.70 | RAD52 (0.44) | SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11082781 | 0.70 | KDM4E (0.47) | KDM4ETSHRALOX15SMN1; SMN2HTT | |
| SCHEMBL11090325 | 0.70 | KDM4E (0.48) | KDM4ESMN1; SMN2HTTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234931-B1 | AZAANTHRACENE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-06-27 | — | — | EP | claimed |
| EP-0234931-A1 | Azaanthracene compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1987-09-02 | — | — | EP | claimed |
| EP-0234931-B1 | AZAANTHRACENE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234931-A1 | Azaanthracene compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1987-09-02 | — | — | EP | disclosed |