SCHEMBL10370537

SCHEMBL10370537

CCOC(=O)c1c(O)c2ccccc2c2nc3ncccc3nc12

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
LMNA P02545 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 5/20 0.44
CFTR P13569 2/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.42
IDO1 P14902 1/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11041020 0.88 ALDH1A1 (0.54) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10370476 0.84 ALDH1A1 (0.45) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10370567 0.82 KDM4E (0.44) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10760248 0.81 KDM5A (0.49) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10370329 0.81 KDM5A (0.49) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10872132 0.78 RAB9A (0.54) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10873276 0.78 ALDH1A1 (0.45) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL3393412 0.77 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10872419 0.76 MEN1 (0.51) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL11072195 0.76 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234931-B1 AZAANTHRACENE COMPOUNDS TAISHO PHARMACEUTICAL CO. LTD (JP) 1990-06-27 EP disclosed
EP-0234931-A1 Azaanthracene compounds TAISHO PHARMACEUTICAL CO. LTD (JP) 1987-09-02 EP disclosed