Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852953 | 0.85 | HPGD (0.50) | EPHX1FAAHKMT2AMEN1HPGD | |
| SCHEMBL6190098 | 0.78 | ALOX15 (0.56) | ALOX15TSHREPHX1EPHX2FAAH | |
| SCHEMBL21730544 | 0.77 | ALOX15 (0.46) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL3417010 | 0.77 | ALOX15 (0.64) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL24584907 | 0.77 | ALOX15 (0.55) | ALOX15TSHREPHX1EPHX2FAAH | |
| SCHEMBL7656762 | 0.77 | EPHX1 (0.50) | EPHX1KMT2AMEN1GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL28551740 | 0.75 | ALOX15 (0.62) | ALOX15TSHREPHX1EPHX2KDM1A | |
| Hydrochloric Acid SCHEMBL27754601 | 0.75 | ALOX15 (0.54) | ALOX15TSHREPHX1EPHX2FAAH | |
| SCHEMBL6189244 | 0.75 | ALOX15 (0.53) | ALOX15TSHREPHX1EPHX2FAAH | |
| SCHEMBL21551277 | 0.74 | ALOX15 (0.56) | ALOX15TSHREPHX1EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199400-B1 | Substituted N-[(4-piperidinyl)alkyl] bicyclic condensed ozazol- and thiazolamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-09-26 | — | — | EP | disclosed |
| US-4826848-A | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-05-02 | — | — | US | disclosed |
| US-4749702-A | PARKINSON*S DISEASE, ENTEROKINESIA | JANSSEN PHARMACEUTICA N. V. (BE) | 1988-06-07 | — | — | US | disclosed |
| US-4689330-A | PARKINSON DISEASE | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-08-25 | — | — | US | disclosed |
| EP-0199400-A2 | Substituted N-[(4-piperidinyl)alkyl] bicyclic condensed ozazol- and thiazolamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-10-29 | — | — | EP | disclosed |