Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17601675 | 0.80 | PTGIR (0.52) | PTGIRHCAR2NPSR1POLBTRPM8 | |
| SCHEMBL2092268 | 0.79 | RAB9A (0.53) | PTGIRNPSR1POLBTSPOTRPM8 | |
| SCHEMBL27839968 | 0.77 | HCAR2 (0.48) | PTGIRHCAR2TSPOKMT2AMEN1 | |
| M-Xylene SCHEMBL29227716 | 0.77 | RAB9A (0.50) | PTGIRNPSR1POLBTSPOTRPM8 | |
| SCHEMBL4283231 | 0.76 | TAS2R14 (0.46) | PTGIRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL2091758 | 0.76 | TRPM8 (0.56) | PTGIRNPSR1POLBTRPM8KMT2A | |
| SCHEMBL19778 | 0.75 | NPSR1 (0.70) | NPSR1POLBTRPM8KMT2ATSHR | |
| SCHEMBL23322924 | 0.73 | PTGIR (0.77) | PTGIR | |
| Methylamine SCHEMBL10655180 | 0.73 | NPSR1 (0.61) | NPSR1POLBTRPM8KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL5094831 | 0.73 | NPSR1 (0.67) | NPSR1POLBTRPM8KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276736-A1 | 4- [3- (ARYLOXY) BENZYLIDEN]-3-METHYL PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | Pfizer Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2276737-A1 | 4- [3- (ARYLOXY) BENZYLIDENE]-3-METHYL PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | Pfizer Inc. (US) | 2011-01-26 | — | — | EP | disclosed |