Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | SELE | P16581 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247114 | 0.91 | MPO (0.56) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL10372978 | 0.87 | MPO (0.52) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL6440669 | 0.86 | MPO (0.69) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL6568247 | 0.85 | MPO (0.51) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL8767124 | 0.85 | MPO (0.68) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL6568264 | 0.83 | SENP5 (0.49) | MPOCYSLTR1ICAM1SELESCD | |
| SCHEMBL6568274 | 0.82 | MPO (0.51) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL9246108 | 0.79 | MPO (0.48) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL6568731 | 0.78 | MPO (0.59) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL6811772 | 0.78 | EDNRA (0.48) | MPOCYSLTR1ICAM1SELEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | claimed |
| EP-0187487-A1 | Benzothiophenes and benzofurans having antiallergic activity | WARNER-LAMBERT COMPANY (US) | 1986-07-16 | — | — | EP | claimed |