Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371772 | 0.68 | PDE3B (0.56) | TSHR | |
| SCHEMBL26003452 | 0.57 | ALDH1A1 (0.50) | HSD17B10 | |
| SCHEMBL34469977 | 0.57 | NOTUM (0.50) | — | |
| SCHEMBL34469705 | 0.55 | KDM4E (0.50) | TSHRHSD17B10 | |
| SCHEMBL25357326 | 0.52 | GAA (0.55) | — | |
| SCHEMBL9512632 | 0.51 | CA12 (0.45) | PTGS2 | |
| SCHEMBL368155 | 0.51 | CA12 (0.69) | HSD17B10 | |
| SCHEMBL23147088 | 0.50 | LMNA (0.55) | HSD17B10 | |
| SCHEMBL28433852 | 0.50 | HSD17B10 (0.66) | TSHRHSD17B10 | |
| SCHEMBL19511938 | 0.50 | KDM4E (0.54) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231744-B1 | SUBSTITUTED PYRROL-1-YLPHENYLDIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1990-05-30 | — | — | EP | disclosed |