Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 14/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27233831 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1CHRM3SLC6A9CHRM4 | |
| SCHEMBL27233824 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1CHRM3SLC6A9CHRM4 | |
| SCHEMBL27233776 | 0.89 | TRPV4 (0.47) | CHRM2CHRM1CHRM3SLC6A9 | |
| SCHEMBL27233820 | 0.89 | TRPV4 (0.47) | CHRM2CHRM1CHRM3SLC6A9 | |
| SCHEMBL27233780 | 0.89 | TRPV4 (0.47) | CHRM2CHRM1CHRM3SLC6A9 | |
| SCHEMBL27233843 | 0.87 | CHRM2 (0.44) | CHRM2CHRM1CHRM3SLC6A9CHRM4 | |
| SCHEMBL27233841 | 0.87 | CHRM2 (0.44) | CHRM2CHRM1CHRM3SLC6A9CHRM4 | |
| SCHEMBL10373050 | 0.85 | SLC6A7 (0.46) | CHRM2CHRM1SLC6A9 | |
| SCHEMBL28966574 | 0.85 | GPR119 (0.47) | CHRM2CHRM1CHRM3SLC6A9CHRM4 | |
| SCHEMBL28966511 | 0.85 | GPR119 (0.47) | CHRM2CHRM1CHRM3SLC6A9CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378938-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115745971-A | PARP7 inhibitor and application thereof | 重庆华森制药股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-0129128-B1 | 2-PYRIMIDINYL-1-PIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Troponwerke GmbH & Co. KG (DE) | 1990-11-22 | — | — | EP | disclosed |